Bioactive compounds from Hagenia abyssinica with activity against bean pathogenic bacteria

Common bean (Phaseolus vulgaris L.) is a major food crop in Africa and its production plagued by diseases that reduce the potential yield, thus threatening security. This study evaluated compounds from Hagenia abyssinica for bioactivity against bacterial pathogens Xanthomonus axonopodis pv. phaseoli Pseudomonus savastanoi phaseolicola. One triterpenoid, 1,3,19-trihydroxy-2-oxo-12-ursen-28-oic acid (1) two flavans namely, 3,3’,4’,5’-tetrahydroxyflavan (2) 3,3’,4’,5,7-pentahydroxyflavan (3) were isolated bark of H. abyssinica. Structures elucidated based on nuclear magnetic resonance (NMR) high-resolution electrospray ionization mass spectra (HRESIMS) data analysis. These ethyl acetate extract using agar disc diffusion method. The crude showed activity with minimum inhibitory concentrations 1.25 mg/mL. Compound 1 good X. P. phaseolicola 5 mg/mL, respectively, whereas 2 3 modest activity. demonstrated compound have can be used development biopesticides to control diseases.   Key words: Bean pathogens, bioactive compounds, abyssinica, phaseoli,